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Article

Human Leukocyte Antigen-C Genotype and Killer Immunoglobulin-like Receptor-Ligand Matching in Korean Living Donor Liver Transplantation.

Annals of laboratory medicine - 1 Jan 2017

Lee Hyeyoung, Park Ki Hyun, Park Hye Sun, Ryu Ji Hyeong, Lim Jihyang, Kim Yonggoo, Na Gun Hyung, Kim Dong Goo, Oh Eun Jee

Abstract excerpt

BACKGROUND: The interaction between killer immunoglobulin-like receptors (KIRs) and HLA class I regulates natural killer (NK) cell cytotoxicity and function. The impact of NK cell alloreactivity through KIR in liver transplantation remains unelucidated. Since the frequency of HLA-C and KIR genotypes show ethnic differences, we assessed the impact of HLA-C, KIR genotype, or KIR-ligand mismatch on the allograft...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27834065
DOI: 10.3343/alm.2017.37.1.45
PMCID: PMC5107617

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