Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PIRCHE-II Risk and Acceptable Mismatch Profile Analysis in Solid Organ Transplantation.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024

Niemann Matthias, Matern Benedict M, Spierings Eric

Abstract excerpt

To optimize outcomes in solid organ transplantation, the HLA genes are regularly compared and matched between the donor and recipient. However, in many cases a transplant cannot be fully matched, due to widespread variation across populations and the hyperpolymorphism of HLA alleles. Mismatches of the HLA molecules in transplanted tissue can be recognized by immune cells of the recipient, leading to immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Alleles
Share to Epitopes, T-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft Rejection

Share to Histocompatibility Testing

Share to HLA Antigens

Share to Organ Transplantation

Share to Tissue Donors

Source

Identifiers

PMID: 38907898
DOI: 10.1007/978-1-0716-3874-3_12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PIRCHE-II Risk and Acceptable Mismatch Profile Analysis in Solid Organ Transplantation.PMID 38907898Read ↗

PIRCHE-II: an algorithm to predict indirectly recognizable HLA epitopes in solid organ transplantationSemantic proximity Read ↗

Matching donor and recipient based on predicted indirectly recognizable human leucocyte antigen epitopesSemantic proximity Read ↗

Exploratory Study of Predicted Indirectly ReCognizable HLA Epitopes in Mismatched Hematopoietic Cell TransplantationsSemantic proximity Read ↗

PIRCHE application versions 3 and 4 lead to equivalent T cell epitope mismatch scores in solid organ and stem cell transplantation modulesSemantic proximity Read ↗

Computational Approaches to Facilitate Epitope-Based HLA Matching in Solid Organ Transplantation.Semantic proximity Read ↗

The Immunogenicity of HLA Class II Mismatches: The Predicted Presentation of Nonself Allo-HLA-Derived Peptide by the HLA-DR Phenotype of the Recipient Is Associated with the Formation of DSA.Semantic proximity Read ↗

Matchmaker, matchmaker make me a match: Opportunities and challenges in optimizing compatibility of HLA eplets in transplantation.Semantic proximity Read ↗

HLA EPLET Frequencies Are Similar in Six Population Groups and Are Expressed by the Most Common HLA Alleles.Semantic proximity Read ↗

Immunologic risk stratification of pediatric heart transplant patients by combining HLA-EMMA and PIRCHE-IISemantic proximity Read ↗

Enhancing Kidney Transplant Success: Simulation of Prospective Pirche-Ii Molecular Matching in CanadaSemantic proximity Read ↗

Determination of unacceptable HLA antigen mismatches in kidney transplant recipients.Semantic proximity Read ↗

Implementation of molecular matching in transplantation requires further characterization of both immunogenicity and antigenicity of individual HLA epitopes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.