Article
Towards standardisation: comparison of five whole genome sequencing (WGS) analysis pipelines for detection of epidemiologically linked tuberculosis cases.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 1 Dec 2019
Jajou Rana, Kohl Thomas A, Walker Timothy, Norman Anders, Cirillo Daniela Maria, Tagliani Elisa, Niemann Stefan, de Neeling Albert, Lillebaek Troels, Anthony Richard M, van Soolingen Dick
Abstract excerpt
BackgroundWhole genome sequencing (WGS) is a reliable tool for studying tuberculosis (TB) transmission. WGS data are usually processed by custom-built analysis pipelines with little standardisation between them.AimTo compare the impact of variability of several WGS analysis pipelines used internationally to detect epidemiologically linked TB cases.MethodsFrom the Netherlands, 535 Mycobacterium tuberculosis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.