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Progress and pitfalls of gene editing technology in CAR-T cell therapy: a state-of-the-art review

7 Jun 2024

Abstract excerpt

CAR-T cell therapy has shown remarkable promise in treating B-cell malignancies, which has sparked optimism about its potential to treat other types of cancer as well. Nevertheless, the Expectations of CAR-T cell therapy in solid tumors and non-B cell hematologic malignancies have not been met. Furthermore, safety concerns regarding the use of viral vectors and the current personalized production process are...

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PMID: 38912057
DOI: 10.3389/fonc.2024.1388475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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