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Article

Unleashing the Therapeutic Potential of CAR-T Cell Therapy Using Gene-Editing Technologies.

31 Aug 2018

Abstract excerpt

Chimeric antigen receptor (CAR) T-cell therapy, an emerging immunotherapy, has demonstrated promising clinical results in hematological malignancies including B-cell malignancies. However, accessibility to this transformative medicine is highly limited due to the complex process of manufacturing, limited options for target antigens, and insufficient anti-tumor responses against solid tumors. Advances in...

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Identifiers

PMID: 30110720
DOI: 10.14348/molcells.2018.0242

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