Profiling the Expression of Transportome Genes in cancer: A systematic approach

Abstract excerpt

The transportome, the -omic layer encompassing all Ion Channels and Transporters (ICTs), is crucial for cell physiology. It is therefore reasonable to hypothesize a role of the transportome in disease, and in particular in cancer. Here, we present the Membrane Transport Protein DataBase (MTP-DB), a database collecting information on ICTs, and a pipeline that takes expression data and the MTP-DB as input to produc...

Topics

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• Cancer, Hypoxia, and Metabolism
• Cancer, Lipids, and Metabolism
• Drug Design
• Drug Transport and Resistance Mechanisms
• Genomics
• Genotype
• Machine Learning in Bioinformatics
• RNA and protein synthesis mechanisms

Identifiers and source

Literature Corpus work

d4fb2612-c894-5b90-ae0b-e148c4f67f0a

DOI

10.1101/2023.07.18.549498