Article
Submitting Novel Full-Length HLA, MIC, and KIR Alleles with TypeLoader2.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024
Schöne Bianca, Fuhrmann Markus, Surendranath Vineeth, Schmidt Alexander H, Lange Vinzenz, Schöfl Gerhard
Abstract excerpt
The Immuno Polymorphism Database (IPD) plays a pivotal role for immunogenetics. Due to technical limitations, genotyping often focuses on specific key regions like the antigen recognition domain (ARD) for HLA genotyping, and the databases are populated accordingly. More recently, though, modern next generation sequencing (NGS) assays allow using larger gene segments or even complete genes for genotyping. It is...
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