Article
Genetic influence of meningioma on cisplatin resistance: a Mendelian randomization analysis.
International journal of clinical pharmacy - 1 Oct 2024
Yu Kefu, Li Ziming, Shi Weizhong, Yang Shuxian, Zhao Zhigang, Yang Li
Abstract excerpt
BACKGROUND: Although various aspects of cisplatin resistance have been studied, the impact of genetic variations still needs to be explored. AIM: This study aimed to investigate the impact of cisplatin on meningiomas using a two-sample Mendelian randomization (MR) approach, employing genetic variants associated with cisplatin use as instrumental variables. METHOD: We conducted a two-sample MR analysis using...
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