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Article

Exploring the genetic correlation and causal relationships between breast cancer and meningioma using bidirectional Mendelian randomization.

Scientific reports - 4 Feb 2025

Ding Lu, Chen Bo, Zhou Zhou, Mei Zhaojun, Cao Kan, Lu Xinyu, Chen Wei

Abstract excerpt

Previous studies have indicated a significantly higher prevalence of breast cancer (BC) among female patients with meningioma compared to the general female population. Therefore, this study aimed to assess the causal relationship between BC and meningioma at the genetic level. Genetic instrumental variables (IVs) for BC were identified from the Breast Cancer Association Consortium (BCAC), the Discovery Biology...

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Identifiers

PMID: 39905226
DOI: 10.1038/s41598-025-88829-0
PMCID: PMC11794611

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