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Article

Causal Relationship Between Galectins With Neuroblastoma: A Mendelian Randomization Study.

Molecular neurobiology - 22 Nov 2025

Long Chunxi, Liang Ping, Liu Xiaoqin, Wang Yali

Abstract excerpt

Galectins are a family of proteins that are involved in various aspects of cancer, including tumor growth, cell migration, invasion, and metastasis. Galectins are subdivided into three families: prototype (such as Gal-1), chimera type (such as Gal-3), and tandem repeat type (such as Gal-9). Despite the evidence linking galectins to the risk of neuroblastoma (NB), the causal association between galectins and NB...

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Topics

Humans
Mendelian Randomization Analysis
Neuroblastoma
Galectins
Polymorphism, Single Nucleotide
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genome-Wide Association Study

Causality

Risk Factors

Source

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Identifiers

PMID: 41273465
DOI: 10.1007/s12035-025-05494-0
PMCID: PMC12640329

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