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Context-dependent role of sirtuin 2 in inflammation

10 May 2024

Abstract excerpt

Sirtuin 2 is a member of the sirtuin family nicotinamide adenine dinucleotide (NAD+)-dependent deacetylases, known for its regulatory role in different processes, including inflammation. In this context, sirtuin 2 has been involved in the modulation of key inflammatory signaling pathways and transcription factors by deacetylating specific targets, such as nuclear factor κB and nucleotide-binding oligomerization...

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PMID: 38886935
DOI: 10.4103/nrr.nrr-d-23-02063

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