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Sirtuins: The NAD + -Dependent Multifaceted Modulators of Inflammation

28 Sept 2023

Abstract excerpt

Significance: Sirtuins are NAD + -dependent histone deacetylases regulating important processes in cellular biology such as inflammation, metabolism, oxidative stress, and apoptosis. Recent Advances: Despite initially being discovered to regulate transcription and life span via histone deacetylase activities, emerging data continually uncover new targets and propose additional roles. Due to the outstanding...

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PMID: 37767625
DOI: 10.1089/ars.2023.0295

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