Article
M133S mutation possibly involve in the ER stress and mitophagy pathway in maintenance hemodialysis patients with occult hepatitis B infection.
Scientific reports - 17 Jun 2024
Zou Yurong, Chen Sipei, Cui Yiyuan, Zou Yang
Abstract excerpt
Occult hepatitis B virus infection (OBI) is characterized by the presence of HBV DNA in the absence of detectable HBsAg. OBI is an important risk factor for cirrhosis and hepatocellular carcinoma, but its pathogenesis has not been fully elucidated. Mutations in the HBV preS/S genes can lead to impaired secretion of either HBsAg or S-protein resulting in the accumulation of defective viruses or S protein in cells....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
