Article
Association between cathepsins and skin cancers: A bidirectional two-sample Mendelian randomization study.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) - 1 Aug 2024
Ma Xinyi, Zhuang Haocheng, Xu Mingze, Hou Fangzhen, Xue Chunyu
Abstract excerpt
BACKGROUND: Several cathepsins have been identified as being involved in the development of cancer. Nevertheless, the connection between cathepsins and skin cancers remained highly elusive. METHODS: A bidirectional Mendelian randomization (MR) analysis was performed to investigate the causal association between cathepsins and skin malignancies. The genome-wide association studies (GWAS) data for cathepsins,...
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