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Article

Genetic polymorphisms in the 5-HT and endocannabinoid systems moderate the association between childhood trauma and burnout in the general occupational population.

Progress in neuro-psychopharmacology & biological psychiatry - 30 Aug 2024

Li Yuling, Wang Lei, He Yingyi, Zhu Shuanggen, He Shu-Chang, Zhang Xiang Yang

Abstract excerpt

BACKGROUND: Interactions between the serotonin (5-HT) and endocannabinoid (eCB) systems have been reported in the psychopathology of stress-related symptoms, while their interplay in regulating the relationship between childhood trauma and burnout remains unclear. In this study, we investigated the interaction of childhood trauma with genetic polymorphisms in these two systems in predicting burnout. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Receptor, Serotonin, 5-HT2A

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Source

Identifiers

PMID: 38879068
DOI: 10.1016/j.pnpbp.2024.111054

Genes

FAAH
HTR2A
HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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