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Article

Interaction between FKBP5 and childhood trauma and risk of aggressive behavior.

Archives of general psychiatry - 1 Jan 2012

Bevilacqua Laura, Carli Vladimir, Sarchiapone Marco, George Danielle K, Goldman David, Roy Alec, Enoch Mary-Anne

Abstract excerpt

CONTEXT: Childhood trauma may predispose individuals to aggressive behavior, and both childhood trauma and aggressive behavior are associated with hypothalamic-pituitary-adrenal axis dysregulation. OBJECTIVE: To determine whether there would be an interaction between genetic variation in FKBP5 and childhood trauma in predicting aggressive behavior. DESIGN: Cross-sectional study. Four FKBP5 single-nucleotide...

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Source

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Identifiers

PMID: 22213790
DOI: 10.1001/archgenpsychiatry.2011.152
PMCID: PMC3437943

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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