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Article

HDL-cholesterol confers sensitivity of immunotherapy in nasopharyngeal carcinoma via remodeling tumor-associated macrophages towards the M1 phenotype.

Journal for immunotherapy of cancer - 13 Jun 2024

Luo Fan, Cao Jiaxin, Chen Qun, Liu Lusha, Yang Ting, Bai Xue, Ma Wenjuan, Lin Chaozhuo, Zhou Ting, Zhan Jianhua, Huang Yan, Yang Yunpeng, Zhao Hongyun, Zhang Li

Abstract excerpt

BACKGROUND: The sustained effectiveness of anti-programmed cell death protein-1/programmed death-ligand 1 treatment is limited to a subgroup of patients with advanced nasopharyngeal carcinoma (NPC), and the specific biomarker determining the response to immunotherapy in NPC remains uncertain. METHODS: We assessed the associations between pre-immunotherapy and post-immunotherapy serum lipoproteins and survival in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38871480
DOI: 10.1136/jitc-2023-008146
PMCID: PMC11177774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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