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NK cell transfer overcomes resistance to PD-(L)1 therapy in aged mice

9 May 2024

Abstract excerpt

Abstract Background Cancer is the leading cause of death among older adults. Although the integration of immunotherapy has revolutionized the therapeutic landscape of cancer, the complex interactions between age and immunotherapy efficacy remain incompletely defined. Here, we aimed to elucidate the relationship between aging and immunotherapy resistance. Methods Flow cytometry was performed to evaluate the...

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PMID: 38725070
DOI: 10.1186/s40164-024-00511-9

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