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One Health: Therapies Targeting Genetic Variants in Human and Canine Histiocytic and Dendritic Cell Sarcomas.

Veterinary and comparative oncology - 1 Sept 2024

Erich Suzanne Agnes, Teske Erik

Abstract excerpt

The precise cause of HS/DCS is still unknown. The relatively low incidence in humans urges for an animal model with a high incidence to accelerate knowledge about genetics and optimal treatment of HS/DCS. Namely, until now, the therapies targeting genetic variants are still more experimental and sparsely used, while consensus is missing. In addition, the literature about variants and possible mutation-targeted...

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PMID: 38867335
DOI: 10.1111/vco.12988

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