Article
The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2012
Shearin Abigail L, Hedan Benoit, Cadieu Edouard, Erich Suzanne A, Schmidt Emmett V, Faden Daniel L, Cullen John, Abadie Jerome, Kwon Erika M, Gröne Andrea, Devauchelle Patrick, Rimbault Maud, Karyadi Danielle M, Lynch Mary, Galibert Francis, Breen Matthew, Rutteman Gerard R, André Catherine, Parker Heidi G, Ostrander Elaine A
Abstract excerpt
BACKGROUND: Advantages offered by canine population substructure, combined with clinical presentations similar to human disorders, makes the dog an attractive system for studies of cancer genetics. Cancers that have been difficult to study in human families or populations are of particular interest. Histiocytic sarcoma is a rare and poorly understood neoplasm in humans that occurs in 15% to 25% of Bernese...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.