Article
Estimation of SARS-CoV-2 fitness gains from genomic surveillance data without prior lineage classification.
Proceedings of the National Academy of Sciences of the United States of America - 18 Jun 2024
Donker Tjibbe, Papathanassopoulos Alexis, Ghosh Hiren, Kociurzynski Raisa, Felder Marius, Grundmann Hajo, Reuter Sandra
Abstract excerpt
The emergence of SARS-CoV-2 variants with increased fitness has had a strong impact on the epidemiology of COVID-19, with the higher effective reproduction number of the viral variants leading to new epidemic waves. Tracking such variants and their genetic signatures, using data collected through genomic surveillance, is therefore crucial for forecasting likely surges in incidence. Current methods of estimating...
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