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Article

Reevaluating the prognostic role of BRAF mutation in colorectal cancer liver metastases.

American journal of surgery - 1 May 2022

Pikouli Anastasia, Papaconstantinou Dimitrios, Wang Jane, Kavezou Foteini, Pararas Nikolaos, Nastos Constantinos, Pikoulis Emmanouil, Margonis Georgios Antonios

Abstract excerpt

INTRODUCTION: Mutations in the BRAF proto-oncogene have been shown to predict poor patient survival following curative-intent liver surgery for metastatic colorectal cancer. The aim of the present systematic review and meta-analysis is to evaluate the effect of mutated BRAF status (mutBRAF) on the overall (OS) and disease-free survival (DFS) in these patients. METHODS: A comprehensive literature search was...

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Identifiers

PMID: 34544580
DOI: 10.1016/j.amjsurg.2021.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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