Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.

doi:10.1001/jamasurg.2018.0996

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Article

Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.

JAMA surgery - 18 Jul 2018

Margonis Georgios Antonios, Buettner Stefan, Andreatos Nikolaos, Kim Yuhree, Wagner Doris, Sasaki Kazunari, Beer Andrea, Schwarz Christoph, Løes Inger Marie, Smolle Maria, Kamphues Carsten, He Jin, Pawlik Timothy M, Kaczirek Klaus, Poultsides George, Lønning Per Eystein, Cameron John L, Burkhart Richard A, Gerger Armin, Aucejo Federico N, Kreis Martin E, Wolfgang Christopher L, Weiss Matthew J

Abstract excerpt

Importance: BRAF mutations are reportedly associated with aggressive tumor biology. However, in contrast with primary colorectal cancer, the association of V600E and non-V600E BRAF mutations with survival and recurrence after resection of colorectal liver metastases (CRLM) has not been well studied. Objective: To investigate the prognostic association of BRAF mutations with survival and recurrence independently...

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Identifiers

PMID: 29799910
DOI: 10.1001/jamasurg.2018.0996
PMCID: PMC6137519

Genes

BRAF
KRAS

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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