Demystifying BRAF Mutation Status in Colorectal Liver Metastases : A Multi-institutional, Collaborative Approach to 6 Open Clinical Questions.

doi:10.1097/SLA.0000000000005771

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Article

Demystifying BRAF Mutation Status in Colorectal Liver Metastases : A Multi-institutional, Collaborative Approach to 6 Open Clinical Questions.

Annals of surgery - 1 Sept 2023

Margonis Georgios A, Boerner Thomas, Bachet Jean-Baptiste, Buettner Stefan, Moretto Roberto, Andreatos Nikolaos, Sartore-Bianchi Andrea, Wang Jane, Kamphues Carsten, Gagniere Johan, Lonardi Sara, Løes Inger M, Wagner Doris, Spallanzani Andrea, Sasaki Kazunari, Burkhart Richard, Pietrantonio Filippo, Pikoulis Emmanouil, Pawlik Timothy M, Truant Stéphanie, Orlandi Armando, Pikouli Anastasia, Pella Nicoletta, Beyer Katharina, Poultsides George, Seeliger Hendrik, Aucejo Federico N, Kornprat Peter, Kaczirek Klaus, Lønning Per E, Kreis Martin E, Wolfgang Christopher L, Weiss Matthew J, Cremolini Chiara, Benoist Stéphane, D'Angelica Michael

Abstract excerpt

OBJECTIVE: To investigate the clinical implications of BRAF -mutated (mut BRAF ) colorectal liver metastases (CRLMs). BACKGROUND: The clinical implications of mut BRAF status in CRLMs are largely unknown. METHODS: Patients undergoing resection for mut BRAF CRLM were identified from prospectively maintained registries of the collaborating institutions. Overall survival (OS) and recurrence-free survival (RFS) were...

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PMID: 36453261
DOI: 10.1097/SLA.0000000000005771
PMCID: PMC11287877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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