Article
Malignant phyllodes tumor with EGFR variant III mutation: A rare case report with immunohistochemical and genomic studies.
Pathology, research and practice - 1 Jul 2024
Kitazono Ikumi, Akahane Toshiaki, Sasaki Hiromi, Ohi Yasuyo, Shinden Yoshiaki, Takajo Tomoko, Tasaki Takashi, Higashi Michiyo, Noguchi Hirotsugu, Hisaoka Masanori, Tanimoto Akihide
Abstract excerpt
A female in her 60's presented with a left-sided breast mass. A core needle biopsy specimen showed diffuse proliferation of a round cell tumor, which was positive for vimentin, NKX2.2, BCOR, and focal CD99 on immunohistochemistry (IHC). No fusion genes of the Ewing family sarcomas were detected. With a tentative diagnosis of primary breast sarcoma (PBS), total mastectomy was performed after chemotherapy. The...
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