Article
BCOR-CCNB3 Fusion Positive Sarcomas: A Clinicopathologic and Molecular Analysis of 36 Cases With Comparison to Morphologic Spectrum and Clinical Behavior of Other Round Cell Sarcomas.
The American journal of surgical pathology - 1 May 2018
Kao Yu-Chien, Owosho Adepitan A, Sung Yun-Shao, Zhang Lei, Fujisawa Yumi, Lee Jen-Chieh, Wexler Leonard, Argani Pedram, Swanson David, Dickson Brendan C, Fletcher Christopher D M, Antonescu Cristina R
Abstract excerpt
BCOR-CCNB3 sarcoma (BCS) is a recently defined genetic entity among undifferentiated round cell sarcomas, which was initially classified as and treated similarly to the Ewing sarcoma (ES) family of tumors. In contrast to ES, BCS shows consistent BCOR overexpression, and preliminary evidence suggests that these tumors share morphologic features with other tumors harboring BCOR genetic alterations, including BCOR...
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