Article
FoxP3 rs3761548 polymorphism predicts autoimmune disease susceptibility: a meta-analysis.
Human immunology - 1 Dec 2013
He Yanqi, Na Huang, Li Yalun, Qiu Zhixin, Li Weimin
Abstract excerpt
BACKGROUND AND AIMS: Autoimmune diseases (ADs) are associated with loss of self-tolerance leading to immune-mediated destruction of host tissues and organs. FoxP3 polymorphism (-3279 A/C, rs3761548) was shown to associate with AD susceptibility, but the results were inconsistent. This study performed a meta-analysis to investigate the FoxP3 -3279 A/C polymorphism for AD susceptibility. METHODS: A total of eight...
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