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Population genetic polymorphisms of pharmacogenes in Zimbabwe, a potential guide for the safe and efficacious use of medicines in people of African ancestry.

Pharmacogenetics and genomics - 1 Jul 2022

Mbavha Bianza T, Kanji Comfort R, Stadler Nadina, Stingl Julia, Stanglmair Andrea, Scholl Catharina, Wekwete William, Masimirembwa Collen

Abstract excerpt

OBJECTIVE: Pharmacogenomics (PGx) is a clinically significant factor in the safe and efficacious use of medicines. While PGx knowledge is abundant for other populations, there are scarce PGx data on African populations and is little knowledge on drug-gene interactions for medicines used to treat diseases common in Africa. The aim of this study was to use a custom-designed open array to genotype clinically...

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PMID: 35190514
DOI: 10.1097/FPC.0000000000000467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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