Computation-guided engineering of distal mutations in an artificial enzyme.

Abstract excerpt

Artificial enzymes are valuable biocatalysts able to perform new-to-nature transformations with the precision and (enantio-)selectivity of natural enzymes. Although they are highly engineered biocatalysts, they often cannot reach catalytic rates akin those of their natural counterparts, slowing down their application in real-world industrial processes. Typically, their designs only optimise the chemistry inside...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Biocatalysis
• Share to Catalytic Domain