Article
Artificial enzymes bringing together computational design and directed evolution.
Organic & biomolecular chemistry - 11 Mar 2021
Mariz Beatriz de Pina, Carvalho Sara, Batalha Iris L, Pina Ana Sofia
Abstract excerpt
Enzymes are proteins that catalyse chemical reactions and, as such, have been widely used to facilitate a variety of natural and industrial processes, dating back to ancient times. In fact, the global enzymes market is projected to reach $10.5 billion in 2024. The development of computational and DNA editing tools boosted the creation of artificial enzymes (de novo enzymes) - synthetic or organic molecules...
Topics
- Biocatalysis
- Computational Chemistry
- Cycloaddition Reaction
- Directed Molecular Evolution
- Enzymes
- Hydrolysis
- Mutation
- Protein Engineering