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Article

Health economic analysis of polygenic risk score use in primary prevention of coronary artery disease – A system dynamics model

18 May 2024

Abstract excerpt

Background: Primary prevention programs utilising traditional risk scores fail to identify all individuals who suffer acute cardiovascular events. We aimed to model the impact and cost effectiveness of incorporating a Polygenic risk scores (PRS) into the cardiovascular disease CVD primary prevention program in Australia, using a whole-of-system model. Methods: System dynamics models, encompassing acute and...

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PMID: 38828126
DOI: 10.1016/j.ajpc.2024.100672

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