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Article

Polygenic Risk Is Associated With Long-Term Coronary Plaque Progression and High-Risk Plaque.

JACC. Cardiovascular imaging - 1 Dec 2024

Nurmohamed Nick S, Shim Injeong, Gaillard Emilie L, Ibrahim Shirin, Bom Michiel J, Earls James P, Min James K, Planken R Nils, Choi Andrew D, Natarajan Pradeep, Stroes Erik S G, Knaapen Paul, Reeskamp Laurens F, Fahed Akl C

Abstract excerpt

BACKGROUND: The longitudinal relation between coronary artery disease (CAD) polygenic risk score (PRS) and long-term plaque progression and high-risk plaque (HRP) features is unknown. OBJECTIVES: The goal of this study was to investigate the impact of CAD PRS on long-term coronary plaque progression and HRP. METHODS: Patients underwent CAD PRS measurement and prospective serial coronary computed tomography...

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Identifiers

PMID: 39152960
DOI: 10.1016/j.jcmg.2024.06.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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