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Drug Resistance and Epidemiological Success of Modern Mycobacterium tuberculosis Lineages in Western India.

The Journal of infectious diseases - 4 Feb 2025

Dixit Avika, Ektefaie Yasha, Kagal Anju, Freschi Luca, Karyakarte Rajesh, Lokhande Rahul, Groschel Matthias, Tornheim Jeffrey A, Gupte Nikhil, Pradhan Neeta N, Paradkar Mandar S, Deshmukh Sona, Kadam Dileep, Schito Marco, Engelthaler David M, Gupta Amita, Golub Jonathan, Mave Vidya, Farhat Maha

Abstract excerpt

BACKGROUND: Drivers of tuberculosis (TB) transmission in India, the country estimated to carry a quarter of the world's burden, are not well studied. We conducted a genomic epidemiology study to compare epidemiological success, host factors, and drug resistance among the 4 major Mycobacterium tuberculosis (Mtb) lineages (L1-L4) circulating in Pune, India. METHODS: We performed whole-genome sequencing (WGS) of Mtb...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38819323
DOI: 10.1093/infdis/jiae240
PMCID: PMC11793027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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