Article
Strains of Mycobacterium tuberculosis from western Maharashtra, India, exhibit a high degree of diversity and strain-specific associations with drug resistance, cavitary disease, and treatment failure.
Journal of clinical microbiology - 1 Oct 2010
Chatterjee Anirvan, D'Souza Desiree, Vira Tina, Bamne Arun, Ambe Gurish T, Nicol Mark P, Wilkinson Robert J, Mistry Nerges
Abstract excerpt
We performed spoligotyping of Mycobacterium tuberculosis isolates from 833 systematically sampled pulmonary tuberculosis (TB) patients in urban Mumbai, India (723 patients), and adjacent rural areas in western India (110 patients). The urban cohort consisted of two groups of patients, new cases (646 patients) and first-time treatment failures (77 patients), while only new cases were recruited in the rural areas....
Topics
- Adolescent
- Adult
- Aged
- Bacterial Typing Techniques
- Cluster Analysis
- DNA Fingerprinting
- DNA, Bacterial
- Drug Resistance, Bacterial
- Female
- Genotype
- Humans
- India
- Lung