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Article

Gastroesophageal reflux disease and atrial fibrillation: a bidirectional Mendelian randomization study.

International journal of medical sciences - 1 Jan 2024

Chen Xiaoli, Li Aihua, Kuang Yuanyuan, Ma Qilin

Abstract excerpt

Background: In observational studies, gastroesophageal reflux disease (GERD) is linked to atrial fibrillation (AF). It is uncertain whether the relationship is due to GERD-induced AF or GERD caused by AF, or confusion with factors related to GERD and AF such as obesity and sleep-disordered breathing. We applied bidirectional Mendelian randomization (MR), in which genetic variations are used as instrumental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38818473
DOI: 10.7150/ijms.95518
PMCID: PMC11134582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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