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Article

aV integrins and TGF‐β‐induced EMT: a circle of regulation

1 Sept 2011

Abstract excerpt

Abstract EMT and pathogenesis: the good, the bad and the ugly TGF‐b—a central player in EMT Changes in cell–cell/cell–ECM adhesion in EMT—the role of integrins during EMT TGF‐b as a regulator of integrin expression during EMT aV integrins activate TGF‐b ‐ Conformational change activation mechanism ‐ Conformational change activation mechanism with proteolysis TGF‐b and integrin signalling cross‐talk during EMT...

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PMID: 21883891
DOI: 10.1111/j.1582-4934.2011.01419.x

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