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Article

Detection of EGFR exon 20 insertion mutations in non-small cell lung cancer: implications for consistent nomenclature in precision medicine.

Pathology - 1 Aug 2024

Park Jieun, Lee Boram, Song Ji-Young, Sung Minjung, Kwon Mi Jeong, Kim Chae Rin, Lee Sangjin, Shin Young Kee, Choi Yoon-La

Abstract excerpt

Epidermal growth factor receptor (EGFR) exon 20 insertion mutations (E20ins) are the third most frequent mutations observed in non-small cell lung cancer, accounting for approximately 1-10% of all EGFR mutations. In the era of precision medicine and targeted therapies, consistent naming of genetic alterations is crucial to avoid confusion and errors. However, the annotation of EGFR E20ins mutations has been...

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Identifiers

PMID: 38811262
DOI: 10.1016/j.pathol.2024.02.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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