Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD‐mediated pyroptosis in colorectal cancer

28 May 2024

Abstract excerpt

BACKGROUND: Although numerous studies have indicated that activated pyroptosis can enhance the efficacy of antitumour therapy in several tumours, the precise mechanism of pyroptosis in colorectal cancer (CRC) remains unclear. METHODS: Pyroptosis in CRC cells treated with antitumour agents was assessed using various techniques, including Western blotting, lactate dehydrogenase release assay and microscopy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune cells in cancer
Share to Inflammasome and immune disorders
Share to Inflammatory Biomarkers in Disease Prognosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38804602
DOI: 10.1002/ctm2.1692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD‐mediated pyroptosis in colorectal cancerPMID 38804602Read ↗

Inflammasomes and Colorectal CancerSemantic proximity Read ↗

Immune modulation underpins the anti‐cancer activity of HDAC inhibitorsSemantic proximity Read ↗

Inflammasomes Are Influenced by Epigenetic and Autophagy Mechanisms in Colorectal Cancer SignalingSemantic proximity Read ↗

Mechanisms and effects of NLRP3 in digestive cancersSemantic proximity Read ↗

Nuclear translocation of Gasdermin D sensitizes colorectal cancer to chemotherapy in a pyroptosis-independent mannerSemantic proximity Read ↗

Pyroptosis burden is associated with anti-TNF treatment outcome in inflammatory bowel disease: new insights from bioinformatics analysisSemantic proximity Read ↗

NLRC4, inflammation and colorectal cancer (Review).Semantic proximity Read ↗

Histone Deacetylases in the Inflamed Intestinal Epithelium—Promises of New Therapeutic StrategiesSemantic proximity Read ↗

The multifaceted roles of inflammasome proteins in cancerSemantic proximity Read ↗

Role of inflammasomes in cancer immunity: mechanisms and therapeutic potentialSemantic proximity Read ↗

Galangin cooperates with oxaliplatin to inhibit the proliferation and invasion of colorectal cancer cells by targeting CBX3Semantic proximity Read ↗

NLRP3 Inflammasome Activation in Cancer: A Double-Edged SwordSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.