Association of deletion polymorphism rs10573247 in the HMGA2 gene with the risk of breast cancer: bioinformatic and experimental analyses.

doi:10.1186/s12957-024-03415-4

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association of deletion polymorphism rs10573247 in the HMGA2 gene with the risk of breast cancer: bioinformatic and experimental analyses.

World journal of surgical oncology - 28 May 2024

Najibi Kolsoom, Moghanibashi Mehdi, Naeimi Sirous

Abstract excerpt

BACKGROUND: The high mobility group A2 (HMGA2) gene is expressed extensively during early embryonic development but is inactivated in adulthood, and it is also reactivated in various benign and malignant tumors, including breast cancer. We first assessed the potential functional significance of the unstudied deletion polymorphism rs10573247 at the 3'UTR of HMGA2 on miRNA binding using bioinformatic tools, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Computational Biology

Share to Follow-Up Studies

Share to HMGA2 Protein

Share to MicroRNAs

Share to Polymorphism, Restriction Fragment Length

Share to Sequence Deletion

Source

Open in PubMed Open full text

Identifiers

PMID: 38802807
DOI: 10.1186/s12957-024-03415-4
PMCID: PMC11131319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of deletion polymorphism rs10573247 in the HMGA2 gene with the risk of breast cancer: bioinformatic and experimental analyses.PMID 38802807Read ↗

An indel polymorphism in the 3' untranslated region of HMGB1 confers risk for hepatocellular carcinoma by regulating HMGB1 transcriptional activity in a Chinese population.Semantic proximity Read ↗

A functional variant at the miRNA binding site in HMGB1 gene is associated with risk of oral squamous cell carcinoma.Semantic proximity Read ↗

High-mobility group box 1 protein (HMGB1) gene polymorphisms and cancer susceptibility: A comprehensive meta-analysis.Semantic proximity Read ↗

Human HMGA2 promoter is coregulated by a polymorphic dinucleotide (TC)-repeat.Semantic proximity Read ↗

Analysis of miRNAs Targeting 3'UTR of H2AFX Gene: a General in Silico Approach.Semantic proximity Read ↗

HMGB1 genetic polymorphisms are biomarkers for the development and progression of breast cancer.Semantic proximity Read ↗

HMGA1 in cancer: Cancer classification by locationSemantic proximity Read ↗

Emerging roles for HMGA2 in colorectal cancerSemantic proximity Read ↗

Association of Polymorphism rs1045411 in the HMGB1 Gene with Cancer Risk: Evidence from a Meta-analysis.Semantic proximity Read ↗

Role of HMGB1 and its associated signaling pathways in human malignanciesSemantic proximity Read ↗

Roles of HMGA proteins in cancer.Semantic proximity Read ↗

HMGB1: The jack‐of‐all‐trades protein is a master DNA repair mechanicSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.