Article
Risk Factors for Pelvic Organ Prolapse: Wide-Angled Mendelian Randomization Analysis.
International urogynecology journal - 1 Jul 2024
Xiong Zheyu, Yuan Chi, Yang Mengzhu, Wang Menghua, Jian Zhongyu
Abstract excerpt
INTRODUCTION AND HYPOTHESIS: We hypothesized that some metabolic factors, lifestyle factors, and socioeconomic factors may have a causal effect on pelvic organ prolapse (POP). METHODS: We selected instruments from corresponding genome-wide association studies (GWAS), which identified independent single nucleotide polymorphisms strongly associated with 12 potential risk factors. Summary statistics for POP were...
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