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Article

Evaluation for causal effects of socioeconomic traits on risk of female genital prolapse (FGP): a multivariable Mendelian randomization analysis.

BMC medical genomics - 9 Jun 2023

Zhang Wei, Ge Jing, Qu Zhaohui, Wu Wenjuan, Lei Hua, Pan Huiling, Chen Honggu

Abstract excerpt

BACKGROUND: Although observational studies have established some socioeconomic traits to be independent risk factors for pelvic organ prolapse (POP), they can not infer causality since they are easily biased by confounding factors and reverse causality. Moreover, it remains ambiguous which one or several of socioeconomic traits play predominant roles in the associations with POP risk. Mendelian randomization (MR)...

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PMID: 37296408
DOI: 10.1186/s12920-023-01560-5
PMCID: PMC10251634

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