Article
Unveiling the causal link between metabolic factors and ovarian cancer risk using Mendelian randomization analysis.
Frontiers in endocrinology - 1 Jan 2024
Han Li, Xu Shuling, Zhou Dongqi, Chen Rumeng, Ding Yining, Zhang Mengling, Bao Meihua, He Binsheng, Li Sen
Abstract excerpt
Background: Metabolic abnormalities are closely tied to the development of ovarian cancer (OC), yet the relationship between anthropometric indicators as risk indicators for metabolic abnormalities and OC lacks consistency. Method: The Mendelian randomization (MR) approach is a widely used methodology for determining causal relationships. Our study employed summary statistics from the genome-wide association...
Topics
- Humans
- Mendelian Randomization Analysis
- Female
- Ovarian Neoplasms
- Genome-Wide Association Study
- Risk Factors
- Polymorphism, Single Nucleotide