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Article

Genetic Risk of Second Malignant Neoplasm after Childhood Cancer Treatment: A Systematic Review.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2024

Ducos Claire, Aba Naïla, Rosselli Filippo, Fresneau Brice, Al Ahmad Nachar Baraah, Zidane Monia, de Vathaire Florent, Benhamou Simone, Haddy Nadia

Abstract excerpt

Second malignant neoplasm (SMN) is one of the most severe long-term risks for childhood cancer survivors (CCS), significantly impacting long-term patient survival. While radiotherapy and chemotherapy are known risk factors, the observed inter-individual variability suggests a genetic component contributing to the risk of SMN. This article aims to conduct a systematic review of genetic factors implicated in the...

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PMID: 38801411
DOI: 10.1158/1055-9965.EPI-24-0010

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