Article
A conserved KL2-capsule-related phage-resistant mechanism in carbapenem-resistant Acinetobacter baumannii is surmountable by a rationally selected dual-phage cocktail.
Frontiers in cellular and infection microbiology - 1 Jan 2026
Shao Yong, Gao Zhu, You Hongyang, Zhang Shaokun, Zeng Jiaqi, Zhao Jiawei, Yuan Chenyan, Miao Fengqin, Shen Yuqing, Zhang Ying, Liu Ling, Zhang Jianqiong
Abstract excerpt
Introduction: As the use of bacteriophages to combat drug-resistant bacteria increases, phage resistance, which may lead to infection recurrence, has gradually gained attention. The intricate mechanisms underlying phage resistance, which are crucial for improving the efficacy of phage therapy, have not yet been fully delineated. This research focuses on uncovering the mechanisms of phage resistance and...
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