Article
Genetic analysis of interleukin-10 promoter region in patients with systemic lupus erythematosus in Taiwan.
The Kaohsiung journal of medical sciences - 1 Oct 1998
Ou T T, Tsai W C, Chen C J, Chang J G, Yen J H, Wang W S, Lin C H, Tsai J J, Liu H W
Abstract excerpt
Overproduction of interleukin-10 (IL-10) may play an important role in the development of systemic lupus erythematosus (SLE) or lupus nephritis. There is also a polymorphic dinucleotide repeat in the human IL-10 promoter region (IL-10PR). Our aim was to study whether or not the IL-10PR alleles co...
Topics
- Adult
- Aged
- Female
- Genotype
- Humans
- Interleukin-10
- Kidney Failure, Chronic
- Lupus Erythematosus, Systemic
- Lupus Nephritis
- Male
- Middle Aged
- Promoter Regions, Genetic
