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Article

Genetic analysis of interleukin-10 promoter region in patients with systemic lupus erythematosus in Taiwan.

The Kaohsiung journal of medical sciences - 1 Oct 1998

Ou T T, Tsai W C, Chen C J, Chang J G, Yen J H, Wang W S, Lin C H, Tsai J J, Liu H W

Abstract excerpt

Overproduction of interleukin-10 (IL-10) may play an important role in the development of systemic lupus erythematosus (SLE) or lupus nephritis. There is also a polymorphic dinucleotide repeat in the human IL-10 promoter region (IL-10PR). Our aim was to study whether or not the IL-10PR alleles contributed to the susceptibility to SLE or lupus nephritis. One hundred SLE patients and 103 healthy controls were...

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PMID: 9819501

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