Article
Breast cancers in monoallelic MUTYH germline mutation carriers have clinicopathological features overlapping with those in BRCA1 germline mutation carriers.
Breast cancer research and treatment - 1 Feb 2024
Keske Aysenur, Weisman Paul, Ospina-Romero Monica, Raut Prachi, Smith-Simmer Kelcy, Zakas Anna L, Flynn Christopher, Xu Jin
Abstract excerpt
PURPOSE: Breast cancer patients referred to genetic counseling often undergo genetic testing with broad panels that include both breast cancer susceptibility genes as well as genes more specific for extramammary sites. As a result, patients are often incidentally found to have germline mutations in genes that are not necessarily related to breast cancer risk. One such gene is MUTYH. To understand the role MUTYH...
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