Article
Anti-integrin αvβ6 antibody in Takayasu arteritis patients with or without ulcerative colitis.
Frontiers in immunology - 1 Jan 2024
Ishikawa Yuki, Yoshida Hiroyuki, Yoshifuji Hajime, Ohmura Koichiro, Origuchi Tomoki, Ishii Tomonori, Mimori Tsuneyo, Morinobu Akio, Shiokawa Masahiro, Terao Chikashi
Abstract excerpt
Background: It has been well documented that Takayasu arteritis (TAK) and ulcerative colitis (UC) coexist in the same patients. HLA-B*52 characterizes the co-occurrence, which is one of the common genetic features between these two diseases, indicating shared underlying pathologic mechanisms. Anti-integrin αvβ6 antibody (Ab) is present in sera of UC patients in a highly specific manner. We investigated if there...
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