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Article

A genome-wide association study reveals a polygenic architecture of speech-in-noise deficits in individuals with self-reported normal hearing.

Scientific reports - 7 Jun 2024

Bhatt Ishan Sunilkumar, Garay Juan Antonio Raygoza, Bhagavan Srividya Grama, Ingalls Valerie, Dias Raquel, Torkamani Ali

Abstract excerpt

Speech-in-noise (SIN) perception is a primary complaint of individuals with audiometric hearing loss. SIN performance varies drastically, even among individuals with normal hearing. The present genome-wide association study (GWAS) investigated the genetic basis of SIN deficits in individuals with self-reported normal hearing in quiet situations. GWAS was performed on 279,911 individuals from the UB Biobank...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38849415
DOI: 10.1038/s41598-024-63972-2
PMCID: PMC11161523

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