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Article

Causal Relationships Between Relative Intake from the Macronutrients and Alzheimer's Disease: A Two-Sample Mendelian Randomization Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2022

Wang Xiaoxin, Sun Hongru, Pan Sijia, Bai Xiao, Zhu Zhuolin, Zhang Runan, Li Chunlong, Chen Yang, Bao Meitong, Zhang Kewei, Feng Rennan

Abstract excerpt

BACKGROUND: Some observational studies indicated the associations of relative carbohydrate, sugar, fat, and protein intake and Alzheimer's disease (AD). But it remains unclear whether the associations are causal. OBJECTIVE: This study aimed to identify the effects of relative carbohydrate, sugar, fat, and protein intake in the diet on AD. METHODS: A two-sample Mendelian randomization was employed. Finally, 14...

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PMID: 35342086
DOI: 10.3233/JAD-215535

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