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Article

Differential 3D genome architecture and imprinted gene expression: cause or consequence?

Biochemical Society transactions - 26 Jun 2024

Moindrot Benoit, Imaizumi Yui, Feil Robert

Abstract excerpt

Imprinted genes provide an attractive paradigm to unravel links between transcription and genome architecture. The parental allele-specific expression of these essential genes - which are clustered in chromosomal domains - is mediated by parental methylation imprints at key regulatory DNA sequences. Recent chromatin conformation capture (3C)-based studies show differential organization of topologically...

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Identifiers

PMID: 38775198
DOI: 10.1042/BST20230143
PMCID: PMC11346452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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